[Comment] BMI and outcomes in melanoma: more evidence for the obesity paradox

The association between increased body-mass index (BMI) and the risk of developing and dying from cancer has been recognised across a broad range of tumour types.1,2 The magnitude of this association is so great that in the USA obesity is considered to be the major preventable cause of cancer.3 However, data regarding the effect of obesity on the outcomes of patients undergoing cancer treatment is less clear. Several observational studies in different tumour types have shown that a moderately increased BMI (compared with an optimal BMI of 22 ยท5 kg/m2) is associated with improved outcomes both around the time of treatment and in later years of follow-up for several cancers.
Source: The Lancet Oncology - Category: Cancer & Oncology Authors: Tags: Comment Source Type: research