Does volumetric measurement serve as an imaging biomarker for tumor aggressiveness of ameloblastomas?

Ameloblastomas are locally aggressive neoplasms of odontogenic epithelial origin [1]. With approximately 40% of all odontogenic tumors, this neoplastic entity constitutes the most frequent subtype, outnumbering keratocystic odontogenic tumors (KCOT) and odontogenic myxomas [2]. The World Health Organization (WHO) distinguishes the solid/multicystic, extraosseous, desmoplastic and unicystic subtype, each one showing differential clinical, radiological and biological characteristics [3]. The mean age at the time of diagnosis is approximately 36  years with a very broad age range (childhood to late adulthood) [4,5].

Source: Oral Oncology - January 10, 2018 Category: Cancer & Oncology Authors: Ali-Farid Safi, Martin Kauke, Marco Timmer, Andrea Grandoch, Hans-Joachim Nickenig, Elif G ültekin, Reinhard Büttner, Matthias Kreppel, Joachim Zöller Source Type: research