Identification of a gene expression signature predicting survival in oral cavity squamous cell carcinoma using Monte Carlo cross validation

Head and neck cancers are cancers of the upper airway and/or digestive tract found in the oral cavity, laryngeal, pharyngeal, oropharyngeal, and hypo-pharyngeal tissues. Head and neck cancers make up 3% of cancers diagnosed each year [1,2]. Head and neck cancer incidence has declined from 25 cases per 100,000 at risk in the 1990s to 15 cases per 100,000 at risk in the present day [3]. While the decrease in head and neck cancer incidence may be due to a drop in tobacco use [4,5], the mortality associated with these cancers has not changed significantly in the last twenty years [6].
Source: Oral Oncology - Category: Cancer & Oncology Authors: Source Type: research