Refining the eighth edition AJCC TNM classification and prognostic groups for papillary thyroid cancer with lateral nodal metastasis

Papillary thyroid cancer (PTC) is one of the most common cancers, with an incidence rate that continues to rise annually. The cancer is usually indolent with excellent prognosis, but cases with lateral nodal metastasis (N1b) require extended neck surgery and are considered to have relatively poor prognosis [1 –3]. In the seventh American Joint Committee on Cancer (AJCC) TNM staging system, all N1b patients 45 years or older were classified as stage IV regardless of other factors [4,5], and the mortality risk of N1b was therefore exaggerated [6].
Source: Oral Oncology - Category: Cancer & Oncology Authors: Source Type: research