Pitfalls of post-treatment PET after de-intensified chemoradiotherapy for HPV-associated oropharynx cancer: Secondary analysis of a phase 2 trial

The management of the neck after definitive chemoradiation (CRT) for oropharynx cancer has evolved from planned neck dissection for all patients towards imaging-based surveillance, reserving neck dissection only for those with concern for residual disease. The safety of this approach was recently confirmed by Mehanna et al. in a large randomized trial showing equivalent survival, better quality of life [1], and higher cost-effectiveness [2] in patients with N2 disease randomized to surveillance PET vs.

Source: Oral Oncology - February 1, 2018 Category: Cancer & Oncology Authors: Kyle Wang, Terence Z. Wong, Robert J. Amdur, William M. Mendenhall, Nathan C. Sheets, Rebecca Green, Brian D. Thorp, Samip N. Patel, Trevor G. Hackman, Adam M. Zanation, Mark C. Weissler, Bhishamjit S. Chera Source Type: research