Oncologic and functional outcomes of pretreatment tracheotomy in advanced laryngeal squamous cell carcinoma: A multi-institutional analysis

The management of advanced stage laryngeal squamous cell carcinoma (SCCA) continues to be debated. Both the Veteran ’s Affairs (VA) Laryngeal Trial and the Radiation Therapy Oncology Group (RTOG) Trial 91-11 have shown similar survival rates between surgical and non-surgical (organ preservation) cohorts [1,2]. However, there is compelling evidence that the increased treatment of locally advanced laryngeal cance r with chemoradiation is implicated in decreased overall survival when comparing the pre- and post-organ preservation eras [3].

Source: Oral Oncology - February 6, 2018 Category: Cancer & Oncology Authors: Serena A. Byrd, Mary J. Xu, Lauren M. Cass, Daniel J. Wehrmann, Matthew Naunheim, Kara Christopher, John J. Dombrowski, Ronald J. Walker, Lori Wirth, John Clark, Paul Busse, Annie Chan, Daniel G. Deschler, Kevin Emerick, Derrick T. Lin, Mark A. Varvares Source Type: research