Proteome analysis reveals that de novo regenerated mucosa over fibula flap-reconstructed mandibles resembles mature keratinized oral mucosa

Attached gingiva and fixed keratinized alveolar mucosa are anatomically peculiar entities that are only seen around the alveolar process of dentulous patients and on the crestal ridges of edentulous patients respectively. In patients who need to undergo segmental resection of the jaws for the treatment of pathologies, composite reconstruction is frequently performed with the free fibula flap. Mandibular bony defects are reconstructed using the fibula bone, external skin is replaced with the lateral leg skin, and dental rehabilitation is provided with implant-supported prosthesis [1 –3].
Source: Oral Oncology - Category: Cancer & Oncology Authors: Source Type: research