Neck recurrence in clinically node-negative oral cancer: 27-year experience at a single institution

The incidence of oral squamous cell carcinoma (OSCC) has gradually increased during the last 4 decades [1]. Despite advances in surgical techniques, radiation therapy (RT), and systemic agents, 5-year overall survival (OS) has plateaued at 65% [2]. With the exception of prevention measures and early-detection educational initiatives, there have been no major changes in the management of patients with OSCC, which is primarily surgical [3,4]. Disease-specific survival (DSS) and OS, are, in large part, dependent on achieving local and regional control [5].
Source: Oral Oncology - Category: Cancer & Oncology Authors: Source Type: research