Diffusion tensor imaging correlates of early markers of depression in youth at high ‐familial risk for bipolar disorder

ConclusionsThese results suggest that decreased FA is related to the presence of familial risk for mood disorder along with subdiagnostic symptoms at the time of scanning rather than predictive of subsequent diagnosis. Due to the difficulties performing such longitudinal prospective studies, we note, however, that this latter analysis may be underpowered due to sample size within the high‐risk MDD group. Further clinical follow‐up may clarify these findings.

Source: Journal of Child Psychology and Psychiatry - February 28, 2018 Category: Psychiatry Authors: Rossana Ganzola, Andrew M. McIntosh, Thomas Nickson, Emma Sprooten, Mark E. Bastin, Stephen Giles, Alix Macdonald, Jessika Sussmann, Simon Duchesne, Heather C. Whalley Tags: Original Article Source Type: research