Depression is associated with dimensional and categorical effects on white matter pathways

ConclusionAnhedonia was positively correlated with reduced FA and increased RD in white matter pathways that connect regions critical for value coding, representing stimulus‐reward associations, and guiding value‐based action selection. Thus, a cardinal symptom of MDD—anhedonia—was lawfully related to abnormalities in reward network connectivity.

Source: Depression and Anxiety - February 1, 2018 Category: Psychiatry Authors: Daniel G. Dillon, Atilla Gonenc, Emily Belleau, Diego A. Pizzagalli Tags: RESEARCH ARTICLE Source Type: research