rpoB gene mutations among Mycobacterium tuberculosis isolates from extrapulmonary sites

This study demonstrated sequence alterations in codon 513 of the 81 bp region of the rpoB gene as the most common mutation occurred in 75.6% of molecularly confirmed rifampin‐resistant strains. In addition, simultaneous mutation at codons 512 and 513 was demonstrated in 34.3% of the isolates.

Source: APMIS - February 27, 2018 Category: Research Authors: Azar Dokht Khosravi, Hossein Meghdadi, Ata A. Ghadiri, Ameneh Alami, Amir Hossein Sina, Mehdi Mirsaeidi Tags: Original Article Source Type: research