The tumour glyco-code as a novel immune checkpoint for immunotherapy

Nature Reviews Immunology 18, 204 (2018).
doi:10.1038/nri.2018.3

Authors: Ernesto RodrÍguez, Sjoerd T. T. Schetters & Yvette van Kooyk
Tumour growth is accompanied by tumour evasion of the immune system, a process that is facilitated by immune checkpoint molecules such as programmed cell death protein 1 (PD1). However, the role of tumour glycosylation in immune evasion has mostly been overlooked, despite the fact that

Source: Nature Reviews Immunology - February 5, 2018 Category: Allergy & Immunology Authors: Ernesto Rodr Í guez Sjoerd T. T. Schetters Yvette van Kooyk Tags: Perspectives Source Type: research