Towards personalized, tumour-specific, therapeutic vaccines for cancer

Nature Reviews Immunology 18, 168 (2018). doi:10.1038/nri.2017.131 Authors: Zhuting Hu, Patrick A. Ott & Catherine J. Wu Cancer vaccines, which are designed to amplify tumour-specific T cell responses through active immunization, have long been envisioned as a key tool of effective cancer immunotherapy. Despite a clear rationale for such vaccines, extensive past efforts were unsuccessful in mediating clinically relevant antitumour activity in
Source: Nature Reviews Immunology - Category: Allergy & Immunology Authors: Tags: Review Source Type: research