Scrub typhus diagnosis on acute specimens using serological and molecular assays – a three-year prospective study

Scrub typhus (ST) is an underdiagnosed acute febrile illness in the Asia pacific region with recent reemergence. Clinical diagnosis is difficult and laboratory confirmation is largely based on serological and molecular tests. However, WFT still remains the only test available in much of the rural tropics where disproportionate number of cases occur. Sensitive and affordable assays are important for broader use and accurate diagnosis. We evaluated the diagnostic capabilities of serological and molecular assays on single acute clinical samples.

Source: Diagnostic Microbiology and Infectious Disease - February 24, 2018 Category: Microbiology Authors: Munegowda Koralur, Rahul Singh, Muralidhar Varma, Shalini Shenoy, Vasudeva Acharya, Asha Kamath, John Stenos, Eugen Athan, Indira Bairy Source Type: research