Use of the intramuscular route to administer pentamidine isethionate in Leishmania guyanensis cutaneous leishmaniasis increases the risk of treatment failure

New world cutaneous leishmaniasis (NWCL) can be found in French Guiana as well as in several other parts of Central and South America. Leishmania guyanensis accounts for nearly 90% of cases in French Guiana and is treated with pentamidine isethionate, given by either intramuscular or intravenous injection. The military population is particularly exposed due to repeated missions in the rainforest. The purpose of the present study was to identify the factors associated with pentamidine isethionate treatment failure in a series of service members with L.

Source: Travel Medicine and Infectious Disease - February 23, 2018 Category: Infectious Diseases Authors: Jacques-Robert Christen, Eliane Bourreau, Magalie Demar, Edward Lightburn, Pierre Couppi é, Marine Ginouvès, Ghislaine Prévot, Jean-Pierre Gangneux, Hélène Savini, Frank de Laval, Vincent Pommier de Santi, Sébastien Briolant Source Type: research