Clinical manifestations of pachychoroid may be secondary to pachysclera and increased scleral rigidity

Current imaging advancements have led to emergence of pachychoroid as an association of important vision threatening diseases like chronic serous chorioretinopathy and polypoidal choroidal vasculopathy. While the precise relation between thick choroid and such disorder is being investigated, the etiology behind pachychoroid remains elusive. We hypothesize pachychoroid to be a resultant of impeded vascular outflow due to thick sclera and increased scleral rigidity. We discuss our hypothesis in the perspective of other choroidal manifestations of anomalously thick scleral structure.

Source: Medical Hypotheses - February 23, 2018 Category: Biomedical Science Authors: Pradeep Venkatesh, Brijesh Takkar, Shreyas Temkar Source Type: research