The formation of p62 ‐positive inclusion body is associated with macrophage polarization in non‐alcoholic fatty liver disease

ConclusionsThese findings indicate that chronic inflammation by M1‐poralization of macrophages contributes to the disease progression from simple steatosis to NASH in concert with autophagic dysfunction.

Source: Hepatology Research - February 23, 2018 Category: Internal Medicine Authors: Hirofumi Fukushima, Shunhei Yamashina, Atsushi Arakawa, Gentaro Taniguchi, Tomonori Aoyama, Akira Uchiyama, Kazuyoshi Kon, Kenichi Ikejima, Sumio Watanabe Tags: Original Article Source Type: research