Chapter 33 Episodic ataxias

Publication date: 2018 Source:Handbook of Clinical Neurology, Volume 148 Author(s): Joanna C. Jen, Jijun Wan The familial episodic ataxias (EAs) are prototypical channelopathies in the central nervous system clinically characterized by attacks of imbalance and incoordination variably associated with progressive ataxia and variable interictal features. EA1, EA2, and EA6 are caused by mutations in ion channel- and transporter-encoding genes that regulate neuronal excitability and neurotransmission.

Source: Handbook of Clinical Neurology - February 23, 2018 Category: Neurology Source Type: research