Identification and Functional Analysis of a Novel G310D Variant in the Insulin ‐like Growth Factor 1 Receptor (IGF1R) Gene that Associates with Type 2 Diabetes in American Indians

ConclusionA unique G310D variant in IGF1R which occurs in 6% American Indians, may impair IGF1R signaling pathways, thereby increasing risk of T2D.

Source: Diabetes/Metabolism Research and Reviews - February 22, 2018 Category: Endocrinology Authors: Yunhua L. Muller, Graham Skelton, Paolo Piaggi, Peng Chen, Anup Nair, Sayuko Kobes, Wen ‐Chi Hsueh, William C. Knowler, Robert L. Hanson, Leslie J. Baier, Clifton Bogardus Tags: RESEARCH ARTICLE Source Type: research