Circulating PIIINP levels identify adipose tissue ‐associated inflammation in individuals with type 2 diabetes mellitus with and without non‐alcoholic fatty liver disease.

ConclusionsGreater circulating PIIINP levels specifically identify T2DM individuals with AT expansion and systemic pro‐inflammatory profile suggestive for AT dysfunction; our results point towards a new role of PIIINP as a marker of fibro‐inflammation in dysmetabolic conditions, likely related to AT expansion.

Source: Diabetes/Metabolism Research and Reviews - February 1, 2018 Category: Endocrinology Authors: I. Barchetta, F.A. Cimini, R. De Gioannis, G. Ciccarelli, L. Bertoccini, A. Lenzi, M.G. Baroni, M.G. Cavallo Tags: RESEARCH ARTICLE Source Type: research