Electron Cryotomography of Mycoplasma pneumoniae Mutants Correlates Terminal Organelle Architectural Features and Function

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Mycoplasma pneumoniae mutants defective in adherence and gliding were analyzed by electron cryotomography for corresponding changes in terminal organelle architecture. Ultrastructural changes ranged from complete loss of all eleven terminal organelle substructures in some mutants, to changes in specific substructures such as the protein knobs on the terminal organelle surface (green) or the bowl substructure (purple) at its base. Somewhat surprisingly, for other mutants no differences in terminal organelle architecture were evident.

Source: Molecular Microbiology - February 22, 2018 Category: Microbiology Authors: Duncan C. Krause, Songye Chen, Jian Shi, Ashley Jensen, Edward S. Sheppard, Grant J. Jensen Tags: Research Article Source Type: research