Diet control to achieve euglycemia induces significant loss of heart and liver weight via increased autophagy compared with ad libitum diet in diabetic rats.

In conclusion, glycemic control achieved by diet control can prevent hyperglycemia-induced renal hyperplasia in diabetes but may be deleterious even at isocaloric rate when insulin is deficient because of significant loss of heart and liver mass via increased autophagy. PMID: 25168310 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/25168310?dopt=Abstract

Source: exp Mol Med - September 1, 2014 Category: Molecular Biology Authors: Lee JH, Lee JH, Jin M, Han SD, Chon GR, Kim IH, Kim S, Kim SY, Choi SB, Noh YH Tags: Exp Mol Med Source Type: research