Dietary Slowly Digestible Starch Triggers the Gut –Brain Axis in Obese Rats with Accompanied Reduced Food Intake

ConclusionSDS with digestion into the ileum reduced daily food intake and paralleled suppressed expression of appetite‐stimulating neuropeptide genes associated with the gut–brain axis. This novel finding suggests further exploration involving a clinical study and potential development of SDS‐based functional foods as an approach to obesity control. Starch is fabricated in a natural microsphere form to digest slowly and throughout the rat small intestine. Our hypothesis is that starch digested distally will activate enteroendocrine cells to trigger the gut–brain axis to lower appetite and reduce food intake. When fed this slowly digestible starch, diet‐induced obese rats lower gene expression of hypothalamic appetite‐stimulating neuropeptides and eat less food per day. Carbohydrate quality influences the body to affect eating behavior.
Source: Nahrung / Food - Category: Nutrition Authors: Tags: RESEARCH ARTICLE Source Type: research