Fanconi anaemia and cancer: an intricate relationship

Nature Reviews Cancer 18, 168 (2018). doi:10.1038/nrc.2017.116 Authors: Grzegorz Nalepa & D. Wade Clapp Fanconi anaemia (FA) is a genetic disorder that is characterized by bone marrow failure (BMF), developmental abnormalities and predisposition to cancer. Together with other proteins involved in DNA repair processes and cell division, the FA proteins maintain genome homeostasis, and germline mutation of any one
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Tags: Review Source Type: research