Impact of oncogenic pathways on evasion of antitumour immune responses
Nature Reviews Cancer 18, 139 (2018).
doi:10.1038/nrc.2017.117
Authors: Stefani Spranger & Thomas F. Gajewski
Immunotherapeutic interventions are showing effectiveness across a wide range of cancer types, but only a subset of patients shows clinical response to therapy. Responsiveness to checkpoint blockade immunotherapy is favoured by the presence of a local, CD8+ T cell-based immune response within the
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Stefani Spranger Thomas F. Gajewski Tags: Review Source Type: research