Impact of oncogenic pathways on evasion of antitumour immune responses

Nature Reviews Cancer 18, 139 (2018). doi:10.1038/nrc.2017.117 Authors: Stefani Spranger & Thomas F. Gajewski Immunotherapeutic interventions are showing effectiveness across a wide range of cancer types, but only a subset of patients shows clinical response to therapy. Responsiveness to checkpoint blockade immunotherapy is favoured by the presence of a local, CD8+ T cell-based immune response within the
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Tags: Review Source Type: research