Potential role of lipoic acid as a chelator in prevention and treatment of gadolinium brain retention

Gadolinium-based contrast agents (GBCAs) improve diagnostic accuracy of magnetic resonance imaging (MRI) in a wide range of diseases like multiple sclerosis (MS). Gadolinium retention in the brain is a new safety concern regarding the use of GBCAs to enhance MR images [1]. The evidence, and the hypothetical consequences, of long-term retention of gadolinium in the brain after multiple GBCA administrations, particularly with use of linear GBCAs, are controversial [2].
Source: Medical Hypotheses - Category: Biomedical Science Authors: Source Type: research