Vascular dysfunction elicited by a crosstalk between periaortic adipose tissue and the vascular wall is reversed by pioglitazone

ConclusionOur results support the fact that PVAT contributes to the development and progression of cardiovascular disease by underlying mechanisms elicited by ”outside‐in” signalling. Treatment with Pioglitazone may offer a new effect on the whole vessel wall, promoting the stability of advanced atherosclerotic plaques.This article is protected by copyright. All rights reserved.
Source: Cardiovascular Therapeutics - Category: Cardiology Authors: Tags: Original Research Article Source Type: research