Functional 5 ′ UTR mRNA structures in eukaryotic translation regulation and how to find them

Nature Reviews Molecular Cell Biology 19, 158 (2018). doi:10.1038/nrm.2017.103 Authors: Kathrin Leppek, Rhiju Das & Maria Barna RNA molecules can fold into intricate shapes that can provide an additional layer of control of gene expression beyond that of their sequence. In this Review, we discuss the current mechanistic understanding of structures in 5′ untranslated regions (UTRs) of eukaryotic mRNAs and the emerging
Source: Nature Reviews Molecular Cell Biology - Category: Cytology Authors: Tags: Review Source Type: research