Gene expression: AMPK relieves PRC2-mediated silencing

Nature Reviews Molecular Cell Biology 19, 142 (2018). doi:10.1038/nrm.2018.6 Author: Paulina Strzyz AMPK phosphorylates EZH2 — the catalytic subunit of the Polycomb repressive complex 2, thereby inhibiting its gene suppression function and counteracting its tumorigenic effects.

http://dx.doi.org/10.1038/nrm.2018.6

Source: Nature Reviews Molecular Cell Biology - January 24, 2018 Category: Cytology Authors: Paulina Strzyz Tags: Research Highlight Source Type: research

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