Stem cells: A balancing act of lipids
Nature Reviews Molecular Cell Biology 19, 141 (2018).
doi:10.1038/nrm.2018.10
Author: Paulina Strzyz
Perturbation of phospholipid composition in intestinal stem cells (ISCs) results in increased cholesterol biosynthesis; excess cholesterol is a driver of ISC hyperproliferation, and consequently of intestinal hypertrophy and cancer.
Source: Nature Reviews Molecular Cell Biology - Category: Cytology Authors: Paulina Strzyz Tags: Research Highlight Source Type: research
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