Stem cells: A balancing act of lipids

Nature Reviews Molecular Cell Biology 19, 141 (2018). doi:10.1038/nrm.2018.10 Author: Paulina Strzyz Perturbation of phospholipid composition in intestinal stem cells (ISCs) results in increased cholesterol biosynthesis; excess cholesterol is a driver of ISC hyperproliferation, and consequently of intestinal hypertrophy and cancer.
Source: Nature Reviews Molecular Cell Biology - Category: Cytology Authors: Tags: Research Highlight Source Type: research