Mesenchymal –epithelial transition of pancreatic cancer cells at perineural invasion sites is induced by Schwann cells

In conclusion, MET‐like change is induced by Schwann cells, suggesting that Schwann cells contribute to PDAC colonization in pancreatic nerves through activating the MET machinery inside tumor cells in the pancreatic tumor microenvironment.

Source: Pathology International - February 1, 2018 Category: Pathology Authors: Yoko Fujii ‐Nishimura, Ken Yamazaki, Yohei Masugi, Junya Douguchi, Yutaka Kurebayashi, Naoto Kubota, Hidenori Ojima, Minoru Kitago, Masahiro Shinoda, Akinori Hashiguchi, Michiie Sakamoto Tags: Original Article Source Type: research