The combination of TRAIL and MG-132 induces apoptosis in both TRAIL-sensitive and TRAIL-resistant human follicular lymphoma cells

Apoptosis is a type of programmed cell death that plays an essential role in the development and homeostasis of normal tissues. The two main apoptotic pathways are the death receptor pathway (extrinsic pathway) and the mitochondrial pathway (intrinsic pathway). These pathways are executed by caspases which eventually lead to the demise of a cell [1].

Source: Leukemia Research - February 2, 2018 Category: Hematology Authors: Jemal Adem, Mine Eray, Jonna Eeva, Ulla Nuutinen, Jukka Pelkonen Tags: Research paper Source Type: research