MicroRNAs Associated With Reverse Left Ventricular Remodeling in Humans Identify Pathways of Heart Failure Progression [Original Articles]

Conclusions:
Plasma miRNAs associated with LV reverse remodeling in humans are dysregulated in animal HF and target clusters of genes involved in mechanisms implicated in HF. A translational approach integrating human HF, bioinformatics, and model systems may uncover novel pathways involved in HF.

CLINICAL TRIAL REGISTRATION:
URL: https://www.clinicaltrials.gov. Unique identifier: NCT00351390

Source: Circulation: Heart Failure - February 9, 2018 Category: Cardiology Authors: Shah, R., Ziegler, O., Yeri, A., Liu, X., Murthy, V., Rabideau, D., Xiao, C. Y., Hanspers, K., Belcher, A., Tackett, M., Rosenzweig, A., Pico, A. R., Januzzi, J. L., Das, S. Tags: Heart Failure Original Articles Source Type: research