Deleterious Effect of Anti ‐Angiotensin II Type 1 Receptor Antibodies Detected Pretransplant on Kidney Graft Outcomes is Both Proper and Synergistic WITH DONOR‐SPECIFIC ANTI‐HLA ANTIBODIES

ConclusionsAR incidence and graft failure were associated with both DSA and AT1R‐abs. These results demonstrate a proper negative effect of AT1R‐abs on graft outcomes, besides a synergistic one with DSA. Pretransplant AT1R‐abs should be acknowledge to better stratify patients’ immunological risk.

http://onlinelibrary.wiley.com/resolve/doi?DOI=10.1111%2Fnep.13239

Source: Nephrology - February 16, 2018 Category: Urology & Nephrology Authors: Jorge Malheiro, Sandra Tafulo, Leon ídio Dias, La Salete Martins, Isabel Fonseca, Idalina Beirão, António Castro‐Henriques, António Cabrita Tags: Original Article Source Type: research