Glucose effectiveness is a critical pathogenic factor leading to the emergence of glucose intolerance and type 2 diabetes mellitus: an ignored hypothesis.

ConclusionIn “at risk” individuals, a low GE and genetically determined vulnerable β‐cell function are more critical determinants of future glucose intolerance than their preexisting insulin resistant state.

Source: Diabetes/Metabolism Research and Reviews - February 1, 2018 Category: Endocrinology Authors: F.P. Alford, J.E. Henriksen, C. Rantzau, H. Beck ‐Nielsen Tags: COMMENTARY Source Type: research