Effect of metformin on glycaemic control in patients with type 1 diabetes: A meta ‐analysis of randomized controlled trials

ConclusionsCompared with placebo, metformin was not associated with glycaemic control in T1D patients. Although it exhibited other benefits, such as lower BMI and reduced insulin requirements, total cholesterol, and low‐density lipoprotein cholesterol, negative outcomes, such as gastrointestinal adverse effects and severe hypoglycaemia, should also be considered in the use of metformin for T1D patients.

Source: Diabetes/Metabolism Research and Reviews - February 15, 2018 Category: Endocrinology Authors: Haiyang Meng, Ailing Zhang, Yan Liang, Jie Hao, Xiaojian Zhang, Jingli Lu Tags: RESEARCH ARTICLE Source Type: research