Degradation pattern of a porcine collagen membrane in an in vivo model of guided bone regeneration

ConclusionThe collagen membrane investigated was biocompatible and able to promote bone regeneration. However, pronounced signs of degradation were observed starting from day 30. Since successful regeneration is obtained only when cell occlusion and space maintenance exist for the healing time needed by the bone progenitor cells to repopulate the defect, the suitability of collagen membranes in cases where long‐lasting barriers are needed needs to be further reviewed.

Source: Journal of Periodontal Research - February 15, 2018 Category: Dentistry Authors: E. Calciolari, F. Ravanetti, A. Strange, N. Mardas, L. Bozec, A. Cacchioli, N. Kostomitsopoulos, N. Donos Tags: ORIGINAL ARTICLE Source Type: research