Warfarin accelerated vascular calcification and worsened cardiac dysfunction in remnant kidney mice

Conclusion Warfarin treatment contributes to the accelerated vascular calcification in animal models of advanced chronic kidney disease. Clinicians should therefore be aware of the profound risk of warfarin use on vascular calcification and cardiac dysfunction in patients with ESRD and atrial fibrillation.
Source: Journal of the Chinese Medical Association - Category: General Medicine Source Type: research