Partitioning the Pleiotropy Between Coronary Artery Disease and Body Mass Index Reveals the Importance of Low Frequency Variants and Central Nervous System-Specific Functional Elements [Original Articles]

Conclusions: Genome-wide pleiotropy substantially contributes to co-occurrence of CAD and obesity, and it is highly enriched among low frequency variants and central nervous system–specific functional elements.

http://circgenetics.ahajournals.org/cgi/content/short/11/2/e002050?rss=1

Source: Circulation: Cardiovascular Genetics - February 14, 2018 Category: Cardiology Authors: Nikpay, M., Turner, A. W., McPherson, R. Tags: Obesity, Genetics, Coronary Artery Disease Original Articles Source Type: research