Vitamin D modulatory effect on cytokines expression by human gingival fibroblasts and periodontal ligament cells.

CONCLUSIONS: Within the limits of the study, the obtained results support the hypothesis of a modulatory role of VD on periodontal cells exposed to bacterial infection, reducing their inflammatory response and increasing the secretion of anti-inflammatory and modulatory cytokines. Consequently, it could be speculated that Vitamin D assessment, and its possible implementation in deficiency cases, could play a role in periodontal treatment. PMID: 29431349 [PubMed - as supplied by publisher]
Source: Minerva Stomatologica - Category: Dentistry Tags: Minerva Stomatol Source Type: research