Improving Interpretation of Cardiac Phenotypes and Enhancing Discovery With Expanded Knowledge in the Gene Ontology [Original Articles]

Conclusions:
We determined that a combination of curation and ontology development for heart-specific genes and processes supports the identification and downstream analysis of genes responsible for the spread of the cardiac action potential through the heart. Annotating these genes and processes in a structured format facilitates data analysis and supports effective retrieval of gene-centric information about cardiac defects.

Source: Circulation: Cardiovascular Genetics - February 13, 2018 Category: Cardiology Authors: Lovering, R. C., Roncaglia, P., Howe, D. G., Laulederkind, S. J. F., Khodiyar, V. K., Berardini, T. Z., Tweedie, S., Foulger, R. E., Osumi-Sutherland, D., Campbell, N. H., Huntley, R. P., Talmud, P. J., Blake, J. A., Breckenridge, R., Riley, P. R., Lambia Tags: Arrhythmias, Electrophysiology, Functional Genomics Original Articles Source Type: research