Optimisation of antithrombin resistance assay as a practical clinical laboratory test: Development of prothrombin activator using factors Xa/Va and automation of assay

ConclusionWe optimised the ATR assay with the FXa/Va activator and adapted the assay for ACL TOP 500; the assay showed the ability to clearly detect antithrombin‐resistant prothrombin in manual and automated procedures.

Source: Clinical and Laboratory Haematology - February 1, 2018 Category: Hematology Authors: S. Tamura, Y. Suga, M. Tanamura, M. Murata ‐Kawakami, Y. Takagi, Y. Hottori, M. Kakihara, S. Suzuki, A. Takagi, T. Kojima Tags: ORIGINAL ARTICLE Source Type: research