Accumulated Spinal Axial Biomechanical Loading Induces Degeneration in Intervertebral Disc of Mice Lumbar Spine

ConclusionAccumulated spinal axial loading provided by a custom‐made hot plate accelerated mice lumbar disc and especially endplate degeneration. However, this method requires further development to establish a lumbar disc degeneration model.

Source: Orthopaedic Surgery - November 1, 2017 Category: Orthopaedics Authors: Yang ‐jun Lao, Tao‐tao Xu, Hong‐ting Jin, Hong‐feng Ruan, Ji‐tao Wang, Li Zhou, Ping‐er Wang, Jian Wang, Jun Ying, Yuan‐bin Zhang, Cheng Luo, Fang‐da Fu, Pei‐jian Tong, Lu‐wei Xiao, Cheng‐liang Wu Tags: BASIC RESEARCH Source Type: research