Efficacy and safety of antidepressant augmentation of continued antipsychotic treatment in patients with schizophrenia

ConclusionsFor schizophrenia patients on stable antipsychotic treatment, adjunctive antidepressants are effective for total and particularly negative symptom reduction. However, effects are small‐to‐medium, differ across antidepressants, and negative symptom improvement seems restricted to the augmentation of FGAs.

Source: Acta Psychiatrica Scandinavica - February 12, 2018 Category: Psychiatry Authors: B. Galling, J. A. Vernon, A. K. Pagsberg, A. Wadhwa, E. Grudnikoff, A. J. Seidman, M. Tsoy ‐Podosenin, M. Poyurovsky, J. M. Kane, C. U. Correll Tags: Original Article Source Type: research