DNA methylation analyses of the candidate genes identified by a methylome ‐wide association study revealed common epigenetic alterations in schizophrenia and bipolar disorder

ConclusionHypomethylation of FAM63B and IR on chromosome 16 could be common epigenetic risk factors for SZ and BD. Further comprehensive epigenetic studies for BD such as MWAS will uncover the extent of similarity and uniqueness of epigenetic alterations.

Source: Psychiatry and Clinical Neurosciences - January 1, 2018 Category: Neuroscience Authors: Hiroko Sugawara, Yui Murata, Tempei Ikegame, Rie Sawamura, Shota Shimanaga, Yusuke Takeoka, Takeo Saito, Masashi Ikeda, Akane Yoshikawa, Fumichika Nishimura, Yoshiya Kawamura, Chihiro Kakiuchi, Tsukasa Sasaki, Nakao Iwata, Mamoru Hashimoto, Kiyoto Kasai, Tags: Regular Article Source Type: research