Decreased hemodynamic response in inferior frontotemporal regions in elderly with mild cognitive impairment

The verbal fluency task (VFT) is a well-established cognitive marker for mild cognitive impairment (MCI) in the prodromal stage of Alzheimer ´s dementia (AD). The behavioral VFT performance of patients allows the prediction of dementia two years later. But effective compensatory mechanism might cover or reduce the predictive value of the VFT. Therefore the aim of this study is to measure the hemodynamic response during VFT in patients w ith mild cognitive impairments (MCI) to establish the hemodynamic response during the VFT as a screening instrument for the prediction of dementia.
Source: Psychiatry Research: Neuroimaging - Category: Psychiatry Authors: Source Type: research