Sensory nerve degeneration in a mouse model mimicking early manifestations of familial amyloid polyneuropathy due to transthyretin Ala97Ser

ConclusionsThese results demonstrate that the hTTRA97S mouse model develops sensory nerve pathology and corresponding physiology mimicking A97S‐FAP and provides a platform to develop new therapies for the early stage of A97S‐FAP.This article is protected by copyright. All rights reserved.

Source: Neuropathology and Applied Neurobiology - December 1, 2017 Category: Neurology Authors: Hung ‐Wei Kan, Hao Chiang, Whei‐Min Lin, I‐Shing Yu, Shu‐Wha Lin, Sung‐Tsang Hsieh Tags: Original Article Source Type: research