Gastric pH and gastrin levels in chronic renal disease in cats

Chronic kidney disease (CKD) is a common condition, with an overall prevalence rate as high as 50% in older cats. The cause of CKD in cats is often unknown and, therefore, it is difficult to prevent. Thus, clinicians must focus their attention on pharmacologic and dietary management of CKD, which is aimed at slowing disease progression and improving quality of life. Advanced CKD in cats is commonly associated with hyporexia or anorexia, nausea, vomiting, or some combination of these. Gastric erosion and ulceration, typically attributed to direct injury to the gastric mucosa as a result of circulating uremic toxins and gastric hyperacidity, are complications of end-stage renal disease in humans.
Source: Advances in Small Animal Medicine and Surgery - Category: Veterinary Research Tags: Gastroenterology Source Type: research