Treatment of feline oral squamous cell carcinoma with toceranib

Feline oral squamous cell carcinoma (FOSCC) is the most common oral neoplasm in cats, representing>60% of oral tumors in cats. Many treatments have been described. Because of rapid local recurrence or progression, survival times have been poor. Owing to the advanced stage of disease in most cats at the time of diagnosis, surgical resection is rarely possible. Even when possible, mandibulectomy is associated with high morbidity, and local recurrence is seen in>50% of cats. Conventional radiation therapy has shown little benefit as a sole treatment modality, with a median survival time (MST) of 1.5 to 5.5 months.
Source: Advances in Small Animal Medicine and Surgery - Category: Veterinary Research Tags: Oncology Source Type: research