Acute Antiobesity Effects of Intracerebroventricular 11 β‐HSD1 Inhibitor Administration in Diet‐induced obese mice

In conclusion, acute11β‐HSD1 inhibition in hypothalamus could reduce food intake by decreasing ER stress and increasing insulin, leptin, and mammalian target of rapamycin complex 1(mTORC1) signaling.
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Source: Journal of Neuroendocrinology - January 1, 2018 Category: Endocrinology Authors: Minchul Seo, S K M Azizul Islam, Seong ‐Su Moon Tags: Original Article Source Type: research